Products for Research Use Only

LasB-IN-1

CAT: 0931-T208336-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T208336-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Antibacterial, NF-κB, p38 MAPK, Serine Protease
Related Pathways
MAPK, Microbiology/Virology, Proteases/Proteasome, NF-κB
Bioactivity
LasB-IN-1 (compound 5f) is an efficient and orally active inhibitor of LasB (IC50 = 8.7 μM) . It effectively inhibits elastase production and biofilm formation in Pseudomonas aeruginosa, while also attenuating inflammatory responses by downregulating MAPK and NF-κB pathways. LasB-IN-1 holds potential as a candidate agent against drug-resistant infections.
Molecular Formula
C20H22F3NO2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C