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ER? agonist-1

CAT: 0931-T207458-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T207458-01Size: 10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2412715-30-9
Target
Estrogen Receptor/ERR|||Androgen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
ER?agonist-1 (Compound 8) functions as a dual-active selective ER? agonist (EC50: 46.8 nM) and an AR antagonist (IC50: 1555 nM) . By binding to ER?, it activates its signaling pathways while simultaneously inhibiting AR activity. Retaining selective ER? agonist activity in mouse models, ER?agonist-1 is applicable in prostate cancer research.
Smiles
C(CCC(C)C)[C@@]12C(=C3[C@](C)(CC1)C=4C(CC3)=C(C)C(O)=CC4)C[C@@H](O)C2
Molecular Formula
C25H36O2
Molecular Weight
368.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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