ER? agonist-1

• Target:

  Estrogen Receptor/ERR|||Androgen Receptor

• Related Pathways:

  Endocrinology/Hormones

• Bioactivity:

  ER?agonist-1 (Compound 8) functions as a dual-active selective ER? agonist (EC50: 46.8 nM) and an AR antagonist (IC50: 1555 nM) . By binding to ER?, it activates its signaling pathways while simultaneously inhibiting AR activity. Retaining selective ER? agonist activity in mouse models, ER?agonist-1 is applicable in prostate cancer research.

• Smiles:

  C(CCC(C)C)[C@@]12C(=C3[C@](C)(CC1)C=4C(CC3)=C(C)C(O)=CC4)C[C@@H](O)C2

• Molecular Formula:

  C25H36O2

• Molecular Weight:

  368.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2412715-30-9