Amyloid-β-IN-2

CAT: 0931-T207418-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T207418-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1603833-55-1

Target

Beta Amyloid, Gamma-secretase

Related Pathways

Neuroscience, Stem Cells, Proteases/Proteasome

Bioactivity

Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.

Smiles

C(NC1=CC(F)=CC(F)=C1)(=O)C2=CC=3C(N2)=CC=C(C3)[C@@H]4CN(C(C)=O)CCC4

Molecular Formula

C22H21F2N3O2

Molecular Weight

397.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Amyloid-β-IN-2

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