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JR5-26B

CAT: 0931-T207308-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207308-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2446965-04-2
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
JR5-26B is an orally active apoptosis (apoptosis) inducer. It induces cell death via copper-mediated apoptosis and necroptosis (necroptosis) . JR5-26B exhibits antiproliferative activity against MIA PaCa-2, PANC-1, PAN02, SU.86.86, and KPC-2 cells, with IC50 values of 0.6, 4.4, 8.0, 1.1, and 3.4 μM, respectively.
Smiles
N[C@@H]1[C@@]2([C@]1(CN(C2)C=3C=NC(C(NC=4C5=C(C=C(F)C4)C=CC=N5)=O)=CN3)[H])[H]
Molecular Formula
C19H17FN6O
Molecular Weight
364.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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