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SARS-CoV-2 Mpro-IN-44

CAT: 0931-T207266-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207266-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3020713-53-2
Target
Virus Protease, SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
SARS-CoV-2 Mpro-IN-44 (Compound 25) is a broad-spectrum inhibitor of the main protease (Mpro) for coronaviruses. It exhibits inhibitory activity against several high-risk coronaviruses, including SARS-CoV-2 and PEDV, with an IC50 of less than 0.6 μM. The broad inhibition of coronaviruses by SARS-CoV-2 Mpro-IN-44 is achieved through enhanced interaction with conserved sites of Mpro. This compound is a potential candidate for the development of antiviral drugs against coronaviruses.
Smiles
C(N1\C(=N\C2=CC=3C(C=C2Cl)=NN(C)C3)\NC(=O)N(CC=4C(=O)NC=CC4)C1=O)C5=C(OC=6SC(C#N)=CC6)C=C(F)C(Cl)=C5
Molecular Formula
C29H19Cl2FN8O4S
Molecular Weight
665.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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