G-6599

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  G-6599 is a monovalent degrader targeting SMARCA2/A4, with DC50 values of 0.018 nM and 0.056 nM, respectively. It demonstrates degradation activity and antiproliferative effects in AR-dependent prostate cancer cell lines.

• Smiles:

  OC1=CC=CC=C1C=2N=NC(N)=C(C2)N3CC4N(C=5C=CN=C(C#CCCN6CCCCCC6)C5)C(C3)CC4

• Molecular Formula:

  C31H37N7O

• Molecular Weight:

  523.672

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2901806-51-5