β-Glucuronidase-IN-3

CAT: 0931-T206953-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T206953-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3081681-34-4

Target

Others, Antibacterial

Related Pathways

Others, Microbiology/Virology

Bioactivity

β-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric inhibitor targeting β-glucuronidase. It exhibits potent inhibitory activity against Escherichia coli β-glucuronidase (EcGUS) with an IC50 of 12.9 nM. The compound exerts its inhibitory effect through reversible covalent modification of cysteine residues (Cys28, Cys443, and Cys197) on EcGUS. It is applicable in research on gut microbiota-related diseases, particularly in reducing the toxic side effects of Irinotecan and non-steroidal anti-inflammatory drugs (NSAIDs) .

Smiles

O=C1C=2C=CC=CC2[Se]N1C=3C=NNC3

Molecular Formula

C10H7N3OSe

Molecular Weight

264.14

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-173397	β-Glucuronidase-IN-3
HY-E70101-01	α-Glucuronidase
JH917594	β-Glucuronidase
482444	GUSB (Beta-Glucuronidase, Glucuronidase, Beta)
CASAG-K065M	β-Glucuronidase (β-GUS) /β-Glucuronidase (β-G) Assay Kit
BA1300-10	β-Glucuronidase-IN-1
HY-151166	β-Glucuronidase-IN-2
CZM1123-01	Beta-Glucuronidase
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β-Glucuronidase-IN-3

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