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Kv7.2/Kv7.3 modulator-1

CAT: 0931-T206950-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206950-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2981435-42-9
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Kv7.2/Kv7.3 modulator-1 (compound 6a) acts as a modulator for Kv7.2/Kv7.3 channels, with a pEC50 value of 7.96 for opening these channels. Kv7.2/Kv7.3 modulator-1 is applicable in research related to epilepsy, depression, brain injury, and pain.
Smiles
O=C(NCC1=CC=C(F)C=C1)C2=C(N=C(C=C2C)N3CCOCC3)OCC(F)(F)F
Molecular Formula
C20H21F4N3O3
Molecular Weight
427.393
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-[(4-fluorophenyl)methyl]-4-methyl-6-morpholin-4-yl-2-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
CAS Number2981435-42-9
PubChem CID177823053
IUPAC NameN-[(4-fluorophenyl)methyl]-4-methyl-6-morpholin-4-yl-2-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Molecular FormulaC20H21F4N3O3
Molecular Weight427.4
XLogP3.6
Topological Polar Surface Area63.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Heavy Atom Count30
Formal Charge0
Complexity552
SMILES
CC1=CC(=NC(=C1C(=O)NCC2=CC=C(C=C2)F)OCC(F)(F)F)N3CCOCC3
InChI
InChI=1S/C20H21F4N3O3/c1-13-10-16(27-6-8-29-9-7-27)26-19(30-12-20(22,23)24)17(13)18(28)25-11-14-2-4-15(21)5-3-14/h2-5,10H,6-9,11-12H2,1H3,(H,25,28)
InChIKey
CZFSLQHVARJTKP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-[(4-fluorophenyl)methyl]-4-methyl-6-morpholin-4-yl-2-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
CAS: 2981435-42-9
CID: 177823053
Formula: C20H21F4N3O3
MW: 427.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight427.4
XLogP33.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass427.15190419
Monoisotopic Mass427.15190419
Topological Polar Surface Area63.7 Ų
Heavy Atom Count30
Formal Charge0
Complexity552
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
GTR19258148-01Kv7.2/Kv7.3 modulator-1
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GTR19274846-01Kv7.2/Kv7.3 modulator-3
HY-161624Kv7.2 modulator 1
HY-161625Kv7.2 modulator 2
GTR19237824-01Kv7.2/Kv7.3 activator-1
GTR19239727-01Kv7.2/Kv7.3 agonist 1
HY-176715Kv7.2 activator-1
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