Products for Research Use Only

P38α inhibitor 9

CAT: 0013-GTR19258355-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258355-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P38α inhibitor9 (Compound 2015) is a p38α inhibitor that effectively blocks the enzyme activity of p38α, with an IC50 of less than 20 nM. It inhibits MK2T334 phosphorylation and activates Cdc25b and Cdc25c while inactivating Wee1, leading to mitotic catastrophe, aneuploidy or polyploidy, and DNA damage. Additionally, p38α inhibitor9 can suppress colorectal cancer (CRC) metastasis.
CAS Number
2133007-20-0
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC) C1=CC=C2C (=C1) C (=O) C3=CC=C (C=C3CC2) NC4=CC=C (F) C (=C4) NC (=O) C5CC5
Molecular Formula
C27H24FN3O3
Molecular Weight
457.496
Storage Conditions
-20°C
Notes
For research use only.