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KMUP-1

CAT: 0931-T206932-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206932-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
81996-46-5
Target
Guanylate cyclase, PDE, Apoptosis, Potassium Channel
Related Pathways
Apoptosis, GPCR/G Protein, Membrane transporter/Ion channel, Metabolism
Bioactivity
KMUP-1 is a xanthine derivative known for its vasodilatory properties. It functions as a phosphodiesterase (PDE) inhibitor and an activator of soluble guanylate cyclase (sGC), engaging the NO/sGC/cyclic guanosine monophosphate pathway. Additionally, KMUP-1 can open K+ channels and has the potential to alleviate ischemia-induced cardiac myocyte apoptosis (apoptosis) . This compound is useful in cardiovascular and anti-inflammatory research.
Smiles
O=C1C2=C(N=CN2CCN3CCN(C=4C=CC=CC4Cl)CC3)N(C(=O)N1C)C
Molecular Formula
C19H23ClN6O2
Molecular Weight
402.878
Shipping Conditions
Ice Packs
Storage Temperature
-20°C