Tetrafluoro-thalidomide

• Target :

  Ligand for E3 Ligase

• Related Pathways :

  PROTAC

• Bioactivity :

  Tetrafluoro-thalidomide is a fluorinated analog of thalidomide. It acts as an activator of E3 ligase enzymes, facilitating the ubiquitination of proteins for subsequent proteolysis. The structure of tetrafluoro-thalidomide can be further derivatized through fluorine substitution.

• Smiles :

  O=C1C=2C(F)=C(F)C(F)=C(F)C2C(=O)N1C3C(=O)NC(=O)CC3

• Molecular Formula :

  C13H6F4N2O4

• Molecular Weight :

  330.191

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  179033-21-7