Tetrafluoro-thalidomide

• Target:

  Ligand for E3 Ligase

• Related Pathways:

  PROTAC

• Bioactivity:

  Tetrafluoro-thalidomide is a fluorinated analog of thalidomide. It acts as an activator of E3 ligase enzymes, facilitating the ubiquitination of proteins for subsequent proteolysis. The structure of tetrafluoro-thalidomide can be further derivatized through fluorine substitution.

• Smiles:

  O=C1C=2C (F) =C (F) C (F) =C (F) C2C (=O) N1C3C (=O) NC (=O) CC3

• Molecular Formula:

  C13H6F4N2O4

• Molecular Weight:

  330.191

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  179033-21-7