RSK-IN-2

• Target :

  Apoptosis|||S6 Kinase

• Related Pathways :

  PI3K/Akt/mTOR signaling|||Apoptosis|||MAPK

• Bioactivity :

  RSK-IN-2 (Compound 3e) is an inhibitor of RSK, showing IC50 values of 37.89 nM for RSK2, 30.78 nM for RSK1, 20.51 nM for RSK3, and 91.28 nM for RSK4. It suppresses tumor cell proliferation, induces apoptosis, and causes cell cycle arrest at the G2/M phase.

• Smiles :

  O=C(NCCO)C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCN(C)CC4

• Molecular Formula :

  C25H30ClN7O3

• Molecular Weight :

  512.004

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3011713-80-4