Products for Research Use Only
RegisterLogin

GHSR-1a agonist-1

CAT: 0931-T206698-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T206698-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
3060887-25-1
Target
GHSR
Related Pathways
GPCR/G Protein
Bioactivity
GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a) with an EC50 of 0.49 nM. It effectively stimulates the release of endogenous growth hormone by activating GHSR-1a. Doses as low as 0.1 mg/kg (administered orally) can increase body weight and length in 4-week-old rats. GHSR-1a agonist-1 is applicable in research on pediatric growth and developmental delays.
Smiles
C([C@@]12C(=NN(C1=O)C3CC3)CCN(C([C@H](NC(C(C)(C)N)=O)COCC4=CC=CC=C4)=O)C2)C5=CC=CC=C5
Molecular Formula
C30H37N5O4
Molecular Weight
531.646
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-[(2R)-1-[(3aR)-3a-benzyl-2-cyclopropyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide
CAS Number3060887-25-1
PubChem CID177823093
IUPAC NameN-[(2R)-1-[(3aR)-3a-benzyl-2-cyclopropyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide
Molecular FormulaC30H37N5O4
Molecular Weight531.6
XLogP1.7
Topological Polar Surface Area117
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Heavy Atom Count39
Formal Charge0
Complexity951
SMILES
CC(C)(C(=O)N[C@H](COCC1=CC=CC=C1)C(=O)N2CCC3=NN(C(=O)[C@@]3(C2)CC4=CC=CC=C4)C5CC5)N
InChI
InChI=1S/C30H37N5O4/c1-29(2,31)27(37)32-24(19-39-18-22-11-7-4-8-12-22)26(36)34-16-15-25-30(20-34,17-21-9-5-3-6-10-21)28(38)35(33-25)23-13-14-23/h3-12,23-24H,13-20,31H2,1-2H3,(H,32,37)/t24-,30-/m1/s1
InChIKey
VPCWMOIIHNWVCH-AYWVHJORSA-N
Chemical Structure
2D Structure
2D structure of N-[(2R)-1-[(3aR)-3a-benzyl-2-cyclopropyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide
CAS: 3060887-25-1
CID: 177823093
Formula: C30H37N5O4
MW: 531.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight531.6
XLogP31.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Exact Mass531.28455468
Monoisotopic Mass531.28455468
Topological Polar Surface Area117 Ų
Heavy Atom Count39
Formal Charge0
Complexity951
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T38160-01STING Agonist 1a
T78825-01D4R agonist-1
T39797RORγ agonist 1
T210351-01Mincle agonist 1
T209393-01MGluR2 agonist 1
T206978-01LXRα agonist 1
T203516-01RNF5 agonist 1
T200744-01NOD2 agonist 1
T200312-01FOXJ1 agonist 1
T89883-01ACKR3 agonist 1

Alternative Products

CatalogName
HY-173271GHSR-1a agonist-1
MBS5785331STING Agonist 1a
K3906002Ghsr sgRNA CRISPR Lentivector (Mouse) (Target 1)
K0856902GHSR sgRNA CRISPR Lentivector (Human) (Target 1)
036034GHSR, CT (GHSR, Growth hormone secretagogue receptor type 1, GH-releasing peptide receptor, Ghrelin receptor)
abx002152-01Growth Hormone Secretagogue Receptor Type 1 (GHSR) Antibody
036034-BiotinGHSR, CT (GHSR, Growth hormone secretagogue receptor type 1, GH-releasing peptide receptor, Ghrelin receptor) (Biotin)
MBS6302207-01GHSR, CT (GHSR, Growth hormone secretagogue receptor type 1, GH-releasing peptide receptor, Ghrelin receptor) (FITC)
MBS6302214-01GHSR, CT (GHSR, Growth hormone secretagogue receptor type 1, GH-releasing peptide receptor, Ghrelin receptor) (PE)
MBS6302204-01GHSR, CT (GHSR, Growth hormone secretagogue receptor type 1, GH-releasing peptide receptor, Ghrelin receptor) (AP)

Popular Products