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MDH1/2-IN-1

CAT: 0931-T206508-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206508-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2143473-95-2
Target
HIF/HIF Prolyl-Hydroxylase, Dehydrogenase, Mitochondrial Metabolism
Related Pathways
Chromatin/Epigenetic, Metabolism
Bioactivity
MDH1/2-IN-1 is an MDH1/2 inhibitor with IC50 values of 1.07 nM and 1.06 nM, respectively. It suppresses mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 exhibits significant antitumor potential and offers new avenues for developing drugs targeting cancer metabolism.
Smiles
O=C(OC)C=1C=CC=C(C1)NC(=O)CCOC2=CC=C(C=C2)C(C)(C)CC(C)(C)C
Molecular Formula
C25H33NO4
Molecular Weight
411.534
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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