UNC10013

CAT: 0931-T206432-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206432-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
UNC10013 is an allosteric modulator of SETDB1, exhibiting negative allosteric regulation through covalent bond formation with Cys385 on the 3TD domain. It has a kinact/KI value of 1.0 x 10^6 M^-1*s^-1. UNC10013 effectively disrupts SETDB1-mediated Akt methylation, holding potential for application in cancer and neurodegenerative disease research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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