Products for Research Use Only
RegisterLogin

Yck2-IN-1

CAT: 0931-T206070-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T206070-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
401816-26-0
Target
Casein Kinase, Antifungal
Related Pathways
Metabolism, Microbiology/Virology, Stem Cells
Bioactivity
Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 μM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.
Smiles
N#CC=1C=CC2=C(C=3C=CN=CC3)C(=NN2C1)C=4C=CC(F)=CC4
Molecular Formula
C19H11FN4
Molecular Weight
314.316
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T5790-011,1,1,1-Kestohexaose
T83125-01AMPK-α1β1γ1 activator 1
T404761,1,1-Tribromoacetone
T78868-01TWIK-1/TREK-1-IN-1
T391821-Bromo-1,1-dichloroacetone
T391621,1,1,3-Tetrachloroacetone
T73743-011,1′,1′′,1′′′-[1,4-Piperazinediylbis (2,1-ethanediylnitrilo) ]tetrakis[2-dodecanol]
T211817-01C22:1 1-Deoxyceramide (m18:1/22:1)
T209355-01Bfl-1-IN-1
T201451-01HMcl-1-IN-1

Alternative Products

CatalogName
HY-168998Yck2-IN-1
GTR18010539YCK2 Antibody
MBS1255391Recombinant Saccharomyces cerevisiae Casein kinase I homolog 2 (YCK2) , partial
MBS7153834Rabbit anti-Saccharomyces cerevisiae (strain 204508/S288c)(Baker's yeast) YCK2 Polyclonal Antibody
OF59775-011,1,1,1,1-Kestoheptaose
N2864-5.11,1,1,1-Kestohexaose
1120401,1,1,1-Kestohexose
410417-011,1,1-Trichloromethanesulfonic Acid 1,1'-Anhydride
IFA69273-011-Iodobicyclo[1.1.1]pentane
OR3123881-Phenylbicyclo[1.1.1]pentane

Popular Products