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Ferroptosis-IN-8

CAT: 0931-T206031-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T206031-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3056016-82-8
Target
Ferroptosis
Related Pathways
Apoptosis
Purity
0.99831
Bioactivity
Ferroptosis-IN-8 (Compound B4) is a potent and specific small molecule inhibitor of ferroptosis, demonstrating a half-maximal inhibitory concentration (IC50) of 40.49 nM. it suppresses RSL3- or FIN56-induced ferroptosis through robust antioxidant mechanisms, alleviates models of hepatorenal injury, and shows significant potential in preventing a spectrum of ferroptosis-related diseases.
Smiles
O=C(NN=CC1=CC=C(OC)C=C1)C=2C=CC=C(O)C2N
Molecular Formula
C15H15N3O3
Molecular Weight
285.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C