JNJ-9676

• Target:

  DNA/RNA Synthesis|||SARS-CoV

• Related Pathways:

  Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology

• Purity:

  0.9993

• Bioactivity:

  JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, which binds to the membrane protein dimer's transmembrane domain-formed binding pocket, thereby blocking viral assembly and release. It exhibits nanomolar-level antiviral activity against the novel coronavirus and SARS-CoV.

• Smiles:

  C (NC1=CC (C#N) =CC=C1) (=O) C2=C3N (C[C@H] (C) N (C3=O) C4=CC=C (C (F) (F) C5=CC=CC=C5) C=C4) N=C2

• Molecular Formula:

  C28H21F2N5O2

• Molecular Weight:

  497.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3026520-19-1