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Urease-IN-20

CAT: 0931-T205707-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205707-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2998940-98-8
Target
Reactive Oxygen Species, Apoptosis, Antibacterial
Related Pathways
Apoptosis, NF-κB, Immunology/Inflammation, Metabolism, Microbiology/Virology
Bioactivity
Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 μM for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and γH2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.
Smiles
O=C(OC1=N[Se]C=2C=CC=CC12)C=3C=CC=C(F)C3
Molecular Formula
C14H8FNO2Se
Molecular Weight
320.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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