Urease-IN-20

• Target:

  Reactive Oxygen Species|||Apoptosis|||Antibacterial

• Related Pathways:

  Apoptosis|||NF-?B|||Immunology/Inflammation|||Metabolism|||Microbiology/Virology

• Bioactivity:

  Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori), with an IC50 of 0.14 ?M for H. pylori inhibition. It effectively decreases apoptosis in GES-1 cells infected with H. pylori and reduces levels of ROS and ?H2AX. Urease-IN-20 also demonstrates significant gastric mucosal protective effects, making it suitable for H. pylori research.

• Smiles:

  O=C(OC1=N[Se]C=2C=CC=CC12)C=3C=CC=C(F)C3

• Molecular Formula:

  C14H8FNO2Se

• Molecular Weight:

  320.18

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2998940-98-8