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III-31-C

CAT: 0931-T205660-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205660-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
398515-96-3
Target
Gamma-secretase
Related Pathways
Proteases/Proteasome, Stem Cells, Neuroscience
Bioactivity
III-31-C is a (hydroxyethyl) urea γ-secretase inhibitor. It reduces the production of Aऔ, with an IC50 of 10 nM in cell-free γ-secretase assays and 200 nM in APP-transfected cells. III-31-C is applicable for Alzheimer's disease research.
Smiles
N(CC1=CC=CC=C1)(C[C@H]([C@H](CC2=CC=CC=C2)NC(OC(C)(C)C)=O)O)C(N[C@H](C(N[C@H](C(OC)=O)[C@@H](C)C)=O)CC(C)C)=O
Molecular Formula
C35H52N4O7
Molecular Weight
640.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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