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KWR095

CAT: 0931-T205595-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205595-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3057980-16-9
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.
Smiles
O=C(C1=NC=CC=2C=CNC21)N3CCN(C=4C(=O)N5N=C(N=C5N(C4CC)CC(=O)NC6=CC=C(C=C6Cl)C(F)(F)F)C7=CCOCC7)CC3
Molecular Formula
C33H31ClF3N9O4
Molecular Weight
710.105
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-168933KWR095

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