Products for Research Use Only

KWR095

CAT: 0013-GTR19249186-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249186-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KWR095 is a potent, orally bioavailable WRN inhibitor with an IC50 of 0.032 μM against its ATPase activity. It blocks WRN's helicase function, suppressing cancer cell growth in vitro, and is a valuable tool for studying DNA repair mechanisms and synthetic lethality in MSI-H cancer models.
CAS Number
3057980-16-9
Field of Research
Cell Biology, Molecular Biology
Smiles
O=C (C1=NC=CC=2C=CNC21) N3CCN (C=4C (=O) N5N=C (N=C5N (C4CC) CC (=O) NC6=CC=C (C=C6Cl) C (F) (F) F) C7=CCOCC7) CC3
Molecular Formula
C33H31ClF3N9O4
Molecular Weight
710.105
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-168933KWR095