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Tetradifon

CAT: 0931-T20559Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T20559Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
116-29-0
Target
ATPase, Parasite
Related Pathways
Membrane transporter/Ion channel, Microbiology/Virology
Purity
0.9984
Bioactivity
Tetradifon is a broad-spectrum organochlorine acaricide insecticide and a potent inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), a subunit of ATP synthase. Tetradifon is utilized for controlling a variety of mite pests and inhibiting energy-related mitochondrial activities including ADP-stimulated respiration and ATPase activity with an IC50 range of 4.5-27 nmoL/mg mitochondrial protein; it exerts oligomycin-like effects by inhibiting oxidative phosphorylation, inducing significant oxidative stress, and interfering with bone metabolism, making it a compound of interest for researching mitochondrial function, bone remodeling mechanisms, and nephrotoxicity.
Smiles
O=S(=O)(C1=CC=C(Cl)C=C1)C2=CC(Cl)=C(Cl)C=C2Cl
Molecular Formula
C12H6Cl4O2S
Molecular Weight
356.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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