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RSK2-IN-4

CAT: 0931-T205512-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205512-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
62001-32-5
Target
S6 Kinase
Related Pathways
MAPK, PI3K/Akt/mTOR signaling
Bioactivity
RSK2-IN-4 (Compound 10) is an inhibitor of RSK2, showing an inhibition rate of 13.73% on RSK2 activity at a concentration of 10 μM. It binds to the ATP binding site of RSK2 within the NTKD (N-terminal kinase domain), with the electron-donating group at the para position of the phenyl ring being crucial for its inhibitory activity.
Smiles
ClC1=CC=C(C=C1)NCN2N=NC=3C=CC=CC32
Molecular Formula
C13H11ClN4
Molecular Weight
258.706
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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