RSK2-IN-3

• UNSPSC Description:

  RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].

• Target Antigen:

  Ribosomal S6 Kinase (RSK)

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rsk2-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC(C)(C)CO)/C(C#N)=C/C1=CC2=C(NN=C2C3=CC(OC)=C(OC)C(OC)=C3)C=C1

• Molecular Weight:

  450.49

• References & Citations:

  [1]Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13(7):1099-1108.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1627136-54-2