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LYMTAC-2

CAT: 0931-T205010-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205010-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Ras, Kras, Others
Related Pathways
MAPK, Others
Bioactivity
LYMTAC-2 is a lysosome-targeting chimera (LYMTAC) developed to degrade membrane-associated proteins through lysosomal membrane proteins (LMP) such as RNF152, LAPTM4a, and LAPTM5. It forms a ternary complex with target proteins like KRASG12D, facilitating their relocation to lysosomes and resulting in ubiquitin-dependent degradation. This compound has potential for studying membrane protein regulation and devising strategies to counter resistance in KRAS-driven signaling pathways.
Molecular Weight
1248.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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