D-PheTrAP

CAT: 0931-T204969-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T204969-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2241298-26-8

Target

Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

D-PheTrAP is a bisubstrate analog inhibitor of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) . It inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 μM, 2.1 μM, 2.4 μM, and 1.7 μM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively.

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[C@@H](CC1=CC=CC=C1)(C(O)=O)N2C=C(CCOP(C(C)=O)(=O)O)N=N2

Molecular Formula

C15H18N3O6P

Molecular Weight

367.294

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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D-PheTrAP

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