CRX 527

• Target:

  TLR

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.

• Smiles:

  O(C(C[C@H](OC(CCCCCCCCC)=O)CCCCCCCCCCC)=O)[C@@H]1[C@@H](NC(C[C@H](OC(CCCCCCCCC)=O)CCCCCCCCCCC)=O)[C@H](OC[C@H](NC(C[C@H](OC(CCCCCCCCC)=O)CCCCCCCCCCC)=O)C(O)=O)O[C@H](CO)[C@H]1OP(=O)(O)O

• Molecular Formula:

  C81H151N2O19P

• Molecular Weight:

  1488.04

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  216014-14-1