Products for Research Use Only

AMPK-IN-6

CAT: 0931-T204944-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204944-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
AMPK, Autophagy, Apoptosis
Related Pathways
Chromatin/Epigenetic, Apoptosis, PI3K/Akt/mTOR signaling, Autophagy
Bioactivity
AMPK-IN-6 (compound 13a) is a potent AMPK inhibitor with an IC50 value of 0.093 μM. It induces apoptosis and suppresses autophagy. Additionally, AMPK-IN-6 exhibits antiproliferative activity and holds potential for research into pulmonary arterial hypertension.
Smiles
C1CC(CCC1N)NC2=C(C(=O)NC=C2)C3=NC4=C(N3)C=C(C=C4)F
Molecular Formula
C18H20FN5O
Molecular Weight
341.383
Shipping Conditions
Ice Packs
Storage Temperature
-20°C