AMPK-IN-6

• Target:

  AMPK|||Autophagy|||Apoptosis

• Related Pathways:

  Chromatin/Epigenetic|||Apoptosis|||PI3K/Akt/mTOR signaling|||Autophagy

• Bioactivity:

  AMPK-IN-6 (compound 13a) is a potent AMPK inhibitor with an IC50 value of 0.093 µM. It induces apoptosis and suppresses autophagy. Additionally, AMPK-IN-6 exhibits antiproliferative activity and holds potential for research into pulmonary arterial hypertension.

• Smiles:

  C1CC(CCC1N)NC2=C(C(=O)NC=C2)C3=NC4=C(N3)C=C(C=C4)F

• Molecular Formula:

  C18H20FN5O

• Molecular Weight:

  341.383

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C