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Ro4368554

CAT: 0931-T204915-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204915-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
478082-99-4
Target
5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.
Smiles
O=S(=O)(C=1C=CC=CC1)C2=CNC3=C2C=CC=C3N4CCN(C)CC4
Molecular Formula
C19H21N3O2S
Molecular Weight
355.454
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Ro4368554

the selective 5-HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat

CAS Number478082-99-4
PubChem CID6918682
IUPAC Name3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
Molecular FormulaC19H21N3O2S
Molecular Weight355.5
XLogP2.8
Topological Polar Surface Area64.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count25
Formal Charge0
Complexity548
SMILES
CN1CCN(CC1)C2=CC=CC3=C2NC=C3S(=O)(=O)C4=CC=CC=C4
InChI
InChI=1S/C19H21N3O2S/c1-21-10-12-22(13-11-21)17-9-5-8-16-18(14-20-19(16)17)25(23,24)15-6-3-2-4-7-15/h2-9,14,20H,10-13H2,1H3
InChIKey
AOPYPEADLGTXRA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Ro4368554
CAS: 478082-99-4
CID: 6918682
Formula: C19H21N3O2S
MW: 355.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight355.5
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass355.13544809
Monoisotopic Mass355.13544809
Topological Polar Surface Area64.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity548
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-135456Ro4368554

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