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DefNEtTrp

CAT: 0931-T204913-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204913-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Ferroptosis
Related Pathways
Apoptosis
Bioactivity
DefNEtTrp is an iron bis-chelating ligand composed of Def and Trp groups. It demonstrates potent broad-spectrum antiproliferative and cytotoxic effects in cancer cell lines. DefNEtTrp induces apoptosis and ferroptosis, exhibiting cytotoxicity with an IC50 value of 0.77 μM.
Smiles
C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)NCCNC(=S)N/N=C/C5=C(C=CC=N5)N)O
Molecular Formula
C30H27N9O3S
Molecular Weight
593.659
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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