Products for Research Use Only

STEP-IN-1

CAT: 0931-T204907-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204907-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Reactive Oxygen Species, ROS
Related Pathways
Apoptosis, Immunology/Inflammation, Metabolism, NF-κB
Bioactivity
STEP-IN-1 (Compound 14b) is a potent and selective inhibitor of STEP, with an IC50 of 5.27 μM. It offers neuroprotective effects by safeguarding neuronal cells from glutamate-induced toxicity, reducing intracellular reactive oxygen species (ROS) accumulation, and inhibiting apoptosis. STEP-IN-1 is applicable in research related to neurodegenerative diseases.
Smiles
C1=CC2=C(C(=C1)[N+](=O)[O-])C(=O)/C(=C/C3=CC=C(O3)C4=C(C=C(C=C4)C(=O)O)Cl)/C2=O
Molecular Formula
C21H10ClNO7
Molecular Weight
423.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C