STEP-IN-1

• Target:

  Apoptosis|||Reactive Oxygen Species|||ROS

• Related Pathways:

  Apoptosis|||Immunology/Inflammation|||Metabolism|||NF-?B

• Bioactivity:

  STEP-IN-1 (Compound 14b) is a potent and selective inhibitor of STEP, with an IC50 of 5.27 ?M. It offers neuroprotective effects by safeguarding neuronal cells from glutamate-induced toxicity, reducing intracellular reactive oxygen species (ROS) accumulation, and inhibiting apoptosis. STEP-IN-1 is applicable in research related to neurodegenerative diseases.

• Smiles:

  C1=CC2=C(C(=C1)[N+](=O)[O-])C(=O)/C(=C/C3=CC=C(O3)C4=C(C=C(C=C4)C(=O)O)Cl)/C2=O

• Molecular Formula:

  C21H10ClNO7

• Molecular Weight:

  423.76

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C