Products for Research Use Only

PKN3-IN-1

CAT: 0931-T204631-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204631-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2361545-75-5
Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
PKN3-IN-1 (compound 16) inhibits PKN3 (serine/threonine-protein kinase N3) and GAK (cyclin G-associated kinase) with an IC50 of 0.014 μM and a Ki of 0.0044 μM. PKN3-IN-1 is a potential tool compound for investigating the cell biology of PKN3 and its role in pancreatic and prostate cancers, as well as T-cell acute lymphoblastic leukemia.
Smiles
IC=1C=CC=2C(=NC=CC2NC3=CC(OC)=C(OC)C(OC)=C3)C1
Molecular Formula
C18H17IN2O3
Molecular Weight
436.244
Shipping Conditions
Ice Packs
Storage Temperature
-20°C