VDR agonist 3

• Target:

  Vitamin

• Related Pathways:

  Metabolism

• Bioactivity:

  VDR agonist 3 (Compound E15) is a potent activator of the vitamin D receptor (VDR) . It effectively inhibits the activation of hepatic stellate cells (HSC) via VDR. In a model of liver fibrosis induced by CCl4 in mice, VDR agonist 3 significantly alleviates liver fibrosis without causing hypercalcemia.

• Smiles:

  CCC (C1=CC (=CC=C1) OCCCC (CC) (CC) O) OC (=O) C2=C[C@H] ([C@H] ([C@@H] (C2) O) O) O

• Molecular Formula:

  C24H36O7

• Molecular Weight:

  436.538

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C