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VDR agonist 1

CAT: 0931-T13292-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T13292-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2269494-43-9
Target
Vitamin, Apoptosis, Others
Related Pathways
Apoptosis, Others, Metabolism
Bioactivity
VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1].
Smiles
C(CC)(CC)(C=1C=C(C(NCCN(CC)CC)=O)N(CC)C1)C2=CC(C)=C(/C=C/C(CC)(CC)O)C=C2
Molecular Formula
C32H51N3O2
Molecular Weight
509.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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