VDR agonist 1

• Target :

  Vitamin|||Apoptosis|||Others

• Related Pathways :

  Apoptosis|||Others|||Metabolism

• Bioactivity :

  VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1].

• Smiles :

  C(CC)(CC)(C=1C=C(C(NCCN(CC)CC)=O)N(CC)C1)C2=CC(C)=C(/C=C/C(CC)(CC)O)C=C2

• Molecular Formula :

  C32H51N3O2

• Molecular Weight :

  509.77

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2269494-43-9