ELP-004

• Target:

  TRP/TRPV Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.

• Smiles:

  O=C(N(C1=CC=C(Cl)C(Cl)=C1)C)CC

• Molecular Formula:

  C10H11Cl2NO

• Molecular Weight:

  232.106

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  15533-81-0