ELP-004

CAT: 0931-T204534-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T204534-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
15533-81-0
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.
Smiles
O=C(N(C1=CC=C(Cl)C(Cl)=C1)C)CC
Molecular Formula
C10H11Cl2NO
Molecular Weight
232.106
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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