ELP-004

• Target :

  TRP/TRPV Channel

• Related Pathways :

  Membrane transporter/Ion channel

• Bioactivity :

  ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.

• Smiles :

  O=C(N(C1=CC=C(Cl)C(Cl)=C1)C)CC

• Molecular Formula :

  C10H11Cl2NO

• Molecular Weight :

  232.106

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  15533-81-0