Org 274179-0

CAT: 0931-T204377-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T204377-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1421683-12-6

Target

TSH Receptor

Related Pathways

GPCR/G Protein

Bioactivity

Org 274179-0 is an effective allosteric antagonist of the thyroid-stimulating hormone (TSH) receptor, with an IC50 in the nanomolar range. It fully inhibits TSH (and TSI) -mediated activation of the TSH receptor with minimal impact on the efficacy of TSH. This compound can be utilized in studies of Graves' disease (GD) .

Smiles

C[C@@]1(C=2C(N(C(C)=O)CC1)=CC=C(NC(CCC3=CC(C(F)(F)F)=CC=C3)=O)C2)C4=CC=CC=C4

Molecular Formula

C28H27F3N2O2

Molecular Weight

480.521

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T81598-01	Org OD 02-0
T71041-01	Org 9935
T202145-01	ORG-28611
T28262-01	Org-29647
T28265-01	Org-34517
T28258L-01	Org 13011
T33821-01	Org 31258
T50082-01	Org 25543
T28259-01	Org-21465
T23111-01	Org 20599

Alternative Products

Catalog	Name
GTR19250291-01	Org 274179-0
MBS5764524	LysoPC(14:0/0:0)
M22553-01	LysoPC (14:0/0:0)
P31620	TVT7R (0,0)
1209587	Pal-Plato 0.0 - 30.0°
A18797-25	LysoPC (14:0/0:0) 25mg
A18797-10	LysoPC (14:0/0:0) 10mg
A18797-5	LysoPC (14:0/0:0) 5mg
A18797-100	LysoPC (14:0/0:0) 100mg
A18797-50	LysoPC (14:0/0:0) 50mg

Org 274179-0

Related Products

Alternative Products

Popular Products