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Org 274179-0

CAT: 0013-GTR19250291-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250291-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Org 274179-0 is a potent nanomolar allosteric antagonist of the TSH receptor, fully blocking TSH and TSI-induced signaling while largely preserving TSH efficacy. It is a valuable research tool for in vitro and in vivo studies of Graves' disease pathophysiology and receptor mechanism.
CAS Number
1421683-12-6
Field of Research
Pharmacology & Drug Discovery
Smiles
C[C@@]1 (C=2C (N (C (C) =O) CC1) =CC=C (NC (CCC3=CC (C (F) (F) F) =CC=C3) =O) C2) C4=CC=CC=C4
Molecular Formula
C28H27F3N2O2
Molecular Weight
480.521
Storage Conditions
-20°C
Notes
For research use only.

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