PFK-IN-1

CAT: 0931-T204311-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T204311-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

735303-62-5

Target

Parasite

Related Pathways

Microbiology/Virology

Bioactivity

PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.

Smiles

O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=NOC(=C2)C)CC3=CC=C(Cl)C(Cl)=C3

Molecular Formula

C18H15Cl2N3O4S

Molecular Weight

440.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
GTR19250355-01	PFK-IN-1
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sc-44562-PR	PFK-1 (m) -PR
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sc-44561-PR	PFK-1 (h) -PR
sc-44562	PFK-1 siRNA (m)

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