BPN 0026709

• Target :

  Others|||Myosin

• Related Pathways :

  Cytoskeletal Signaling|||Others

• Purity :

  >99.99%

• Bioactivity :

  BPN 0026709?MT-228? is a selective, blood-brain barrier-permeable non-muscle myosin II inhibitor. BPN 0026709 demonstrates enhanced tolerability by preferentially targeting NMIIB (KI = 1.5 ?M) over CMII (KI = 17 ?M), with SmMll MD sharing 83.6% sequence identity with NMllB. BPN 0026709 exhibits sustained efficacy in animal models of stimulant use disorder.

• Smiles :

  O[C@]12C(N(CC1)C=3C=C(OC)N=CC3)=NC=4C(C2=O)=CC(C)=C(C)C4

• Molecular Formula :

  C19H19N3O3

• Molecular Weight :

  337.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2404652-24-8