USP7-IN-16

• Target:

  Others|||DUB

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others|||Ubiquitination

• Bioactivity:

  USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.

• Smiles:

  O=C1C2=C(N(C=C2)C3=CC(OC)=CC(OC)=C3)N=CN1CC4(O)CCN(C(=O)[C@H]5[C@@H](CN(C(=O)C=6SC(=NC6C)C=7C=CC(C)=NC7)CC5)C8=CC=CC=C8)CC4

• Molecular Formula:

  C43H45N7O6S

• Molecular Weight:

  787.93

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2166587-77-3