USP7-IN-4

CAT: 0931-T69820-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T69820-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

2196243-57-7

Target

MDM-2/p53, DUB, p53

Related Pathways

Apoptosis, DNA Damage/DNA Repair, Ubiquitination, Cell Cycle/Checkpoint

Purity

>99.99%

Bioactivity

USP7-IN-4 (USP7 inhibitor ALM4) is a non-competitive, potent and selective inhibitor of USP7 (ubiquitin-specific protease 7) with an IC50 = 6 nM, up-regulates p53 and p21, down-regulates MDM2, increases the level of ubiquitination of MDM2, and exhibits anti-proliferative activity in a variety of cancer cell lines, with an EC50 = 2.0 nM in RS4;11 (acute lymphoblastic leukemia cell line) .

Smiles

CN1C(=C2C(C(=O)N(CC3(O)CCN(C(C[C@@H](C)C4=CC=CC=C4)=O)CC3)C=N2)=N1)C5=CC=C(CN)C=C5

Molecular Formula

C29H34N6O3

Molecular Weight

514.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T4338-01	USP7/USP47 inhibitor
T73234-01	USP7-797
T212441-01	USP7-IN-19
T207128-01	USP7-IN-17
T9217-01	USP7-IN-8
T13271-01	USP7-IN-6
T13270-01	USP7-IN-5
T211314-01	USP7-IN-18
T200500-01	USP7-055
T13268-01	USP7-IN-1

Alternative Products

Catalog	Name
BUP20094-01	USP7-IN-4
339207-01	USP7
BA3902-10	USP7-IN-8
BA2962-10	USP7-IN-9
BA3913-1	USP7-IN-10
10R-6254	USP7 antibody
HY-16709-01	USP7-IN-1
HY-176416	USP7-IN-17
HY-49319	USP7-IN-14
HY-148482-01	USP7-IN-11

USP7-IN-4

Related Products

Alternative Products

Popular Products