IQ-3

CAT: 0931-T8477-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T8477-01Size:1 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
312538-03-7
Target
JNK
Related Pathways
MAPK
Purity
?98%
Bioactivity
IQ3 is a selective inhibitor of JNK3 (JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively) . IQ 3 inhibits NF-?B/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 ?M, also inhibits TNF-? and IL-6 production in vitro.
Smiles
O=C(ON=C1c2ccccc2-c2nc3ccccc3nc12)c1ccco1
Molecular Formula
C20H11N3O3
Molecular Weight
341.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products