Products for Research Use Only

Euphjatrophane M

CAT: 0931-T203551-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203551-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
NF-κB, FOXO, Interleukin, TNF
Related Pathways
Immunology/Inflammation, Apoptosis, NF-κB
Bioactivity
Euphjatrophane M (Compound 6) is a FOXO1 inhibitor that reduces NF-κBp65 phosphorylation and exhibits anti-inflammatory properties. It can inhibit the production of nitric oxide and also suppress the mRNA expression of IL-6, IL-1β, and TNFα in LPS-induced RAW 264.7 macrophages.
Molecular Formula
C20H28O4
Molecular Weight
332.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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