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SPA107

CAT: 0931-T203520-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203520-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
179939-69-6
Target
Others, Microtubule Associated
Related Pathways
Others, Cytoskeletal Signaling
Bioactivity
SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.
Smiles
C([C@@H](C(N[C@H](C(N([C@H](/C=C(/C(OC)=O)\C)C(C)C)C)=O)[C@](C)(C)C)=O)NC)(C)(C)C=1C=2C(N(C)C1)=CC=CC2
Molecular Formula
C31H48N4O4
Molecular Weight
540.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-164923SPA107

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