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MC3343

CAT: 0931-T203345-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T203345-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1535187-91-7
Target
DNA Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9973
Bioactivity
MC3343, a DNMT inhibitor with IC50 values of 5.7 μM for DNMT1 and 1.7 μM for DNMT3a, affects tumor proliferation by blocking osteosarcoma cells in the G1 or G2/M phase and induces osteogenic differentiation by specifically re-expressing genes that regulate this physiological process, and is able to show synergistic effects in combination with adriamycin and cisplatin (CDDP) .
Smiles
O=C(NC=1C=CC=C(C1)NC2=NC(=NC(=C2)C)N)C=3C=CC=C(C3)NC=4C=CN=C5C=CC=CC54
Molecular Formula
C27H23N7O
Molecular Weight
461.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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