IRF1-IN-1

• Target :

  Interleukin|||PARP|||Pyroptosis|||Caspase|||IL Receptor|||IFNAR

• Related Pathways :

  Proteases/Proteasome|||Immunology/Inflammation|||Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity :

  0.9988

• Bioactivity :

  IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor that reduces IRF1 recruitment to the Caspase 1 promoter, inhibiting the cleavage of Caspase 1, GSDMD, IL-1, and PARP1, thereby protecting against skin inflammatory damage.

• Smiles :

  O=C1C=2C=CC=CC2N=CN1CCC(=O)NC3=CC=C(C=C3)S(=O)(=O)N4CCCCC4

• Molecular Formula :

  C22H24N4O4S

• Molecular Weight :

  440.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  701225-07-2