Products for Research Use Only

IRF1-IN-1

CAT: 0931-T203129-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T203129-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
701225-07-2
Target
Interleukin, PARP, Pyroptosis, Caspase, IL Receptor, IFNAR
Related Pathways
Proteases/Proteasome, Immunology/Inflammation, Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9988
Bioactivity
IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor that reduces IRF1 recruitment to the Caspase 1 promoter, inhibiting the cleavage of Caspase 1, GSDMD, IL-1, and PARP1, thereby protecting against skin inflammatory damage.
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O=C1C=2C=CC=CC2N=CN1CCC(=O)NC3=CC=C(C=C3)S(=O)(=O)N4CCCCC4
Molecular Formula
C22H24N4O4S
Molecular Weight
440.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C