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Microtubule destabilizing agent-2

CAT: 0931-T203045-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203045-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Microtubule Associated, Apoptosis, Caspase
Related Pathways
Apoptosis, Proteases/Proteasome, Cytoskeletal Signaling
Bioactivity
Microtubule destabilizing agent-2 (Compound 21) is an orally active and selective anticancer compound targeting microtubule proteins. It disrupts microtubule stability, inhibiting microtubule polymerization. This agent causes human tumor cells to arrest in the G0/G1 phase and induces apoptosis (Apoptosis) through activation of the Caspase cascade pathway. Additionally, it exhibits anti-inflammatory properties, inhibiting the production of TNF-α and IL-6 in vitro. Microtubule destabilizing agent-2 also suppresses tumor growth in xenograft mice.
Molecular Formula
C26H26O4
Molecular Weight
402.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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