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ALKBH5-IN-5

CAT: 0931-T203011-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T203011-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
140481-05-6
Target
ALK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9954
Bioactivity
ALKBH5-IN-5 is a highly selective, potent and covalently binding ALKBH5 inhibitor (IC50 = 0.62 μM) that alters m6A levels on mRNA, promotes differentiation and induces apoptosis, with antitumor activity.ALKBH5 is an N6-methyladenosine (m6A) demethylase that is closely related to leukemogenesis.
Smiles
O=C1C=CC(=O)N1CCC=2C=CC=CC2OC
Molecular Formula
C13H13NO3
Molecular Weight
231.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C