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AUT2

CAT: 0931-T201987-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201987-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1311137-58-2
Bioactivity
AUT2 is a Kv3.1 channel modulator with the potential to treat sensory hyperreactivity in patients with FXS by shifting the activation of high-threshold currents to more negative potentials. This shift reduces high-threshold K+ currents and increases low-threshold K+ currents in neurons, restoring wave IV of the ABR. Due to its ability to regulate neuronal excitability, AUT2 is also promising for the treatment of hearing impairments.
Smiles
O=C1N(C(=O)N[C@@H]1CC)C=2C=CC(OC3=CC(C(C)C)=C(C#N)C=C3)=NC2
Molecular Formula
C20H20N4O3
Molecular Weight
364.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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